Hyperbaric Oxygen Therapy (HBOT) Research for Traumatic Brain Injury (TBI).
Abstract Reactive oxygen species (ROS)-induced mitochondrial abnormalities may have important consequences in the pathogenesis of degenerative diseases and cancer. Vitamin C is an important antioxidant known to quench ROS, but its mitochondrial transport and functions...
Abstract: To investigate whether Hyperbaric Oxygen Therapy (HBO2) could improve neurologic deficits and regional cerebral blood flow (rCBF) in chronic traumatic brain injuries (TBI), the authors employed a nonrandomized control pilot trial. Five subjects, at least...
Abstract: To determine the effect of arousal methods for prolonged coma of 175 patients with severe traumatic brain injury and related factors. There were 175 cases with persistent coma longer than 1 month after severe traumatic brain injury. Coma lasted 1-12 months....
Abstract: Whyte, , , , , , , , (2004). Hyperbaric oxygen for traumatic brain injury. Archives of physical medicine and rehabilitation, 2004 Oct;85(10):1732. https://www.ncbi.nlm.nih.gov/pubmed/15468040
Abstract: Intracranial pressure (ICP) was monitored to evaluate the therapeutic effect of hyperbaric oxygen (HBO(2)) treatment following traumatic brain injury (TBI). This subject is controversial. The aim of our study was to determine whether HBO(2) treatment has a...
Abstract: In the current study, the authors examined the effects of hyperbaric O2 (HBO) following fluid-percussion brain injury and its implications on brain tissue oxygenation (PO2) and O2 consumption (VO2) and mitochondrial function (redox potential). Cerebral...
Abstract: There is mounting evidence both from experimental and clinical studies that traumatic brain injury (TBI) is associated with a reduction of aerobic metabolism. This results from a variable combination of impaired substrate delivery and mitochondrial failure....
Abstract: The growth and progression of traumatic brain injury (TBI) lesions depend significantly on developments in the traumatic penumbra area, perilesional region, where delayed neuronal death occurs. Recent data supports the important role of apoptosis in delayed...
Abstract: To identify the benefits and harms of hyperbaric oxygen therapy (HBOT) to treat traumatic brain injury (TBI). MEDLINE, EMBASE, the Cochrane Library, HealthSTAR, CINAHL, MANTIS, professional society databases, and reference lists. Databases were searched from...