Abstract: Protein tyrosine-phosphatases (PTPs) play important roles in various biological processes. Deregulation in PTP function has been implicated in carcinogenesis and tumour progression in many cancer types. However, the role of protein tyrosine phosphatase...
Cancer
Hyperbaric Oxygen Therapy (HBOT) Research for Cancer.
The efficacy of hyperbaric oxygen therapy related to the clinical stage of osteoradionecrosis of the mandible.
Abstract: This study aimed to evaluate the success of hyperbaric oxygen therapy (HBOT) and surgery in the treatment of mandibular osteoradionecrosis (ORN) in relation to the extent of the ORN. Twenty-seven patients with ORN were identified from a total of 509 patients...
Endoscopic and non-endoscopic approaches for the management of radiation-induced rectal bleeding.
Abstract: Pelvic radiation is a commonly utilized treatment for malignancy of the genitourinary and lower gastrointestinal tract. Radiation proctitis and the resultant clinical picture varies from asymptomatic to potentially life threatening. Similarly, treatment...
Survival, Risk Factors, and Effect of Treatment in 101 Patients With Calciphylaxis.
Abstract: To report on the survival and the associations of treatments upon survival of patients with calciphylaxis seen at a single center. Using the International Classification of Diseases, Ninth Revision diagnosis code of 275.49 and the keyword...
Right cardiac intracavitary metastases from a primary intracranial myxofibrosarcoma.
Abstract: Primary intracranial myxofibrosarcoma is exceedingly rare, with less than 10 cases published. We present a case of a 23-year-old man with previous history of a primary low grade myxofibrosarcoma of the left parietal-occipital convexity resected in March...
Hyperbaric oxygen therapy improves colorectal anastomotic healing.
Abstract: Hyperbaric oxygen treatment (HBOT) has been found to improve the healing of poorly oxygenated tissues. This study aimed to investigate the influence of HBOT on the healing in ischemic colorectal anastomosis. Forty Wistar rats were randomly divided into a...
Hyperbaric oxygen therapy sensitizes nimustine treatment for glioma in mice.
Abstract: Nimustine (ACNU) has antitumor activities in patients with malignant glioma. Hyperbaric oxygen (HBO) may enhance the efficacy of certain therapies that are hampered by the hypoxic microenvironment. We examined the combined effects of ACNU and HBO in a GFP...
Temporomandibular joint involvement as a positive clinical prognostic factor in necrotising external otitis.
Abstract: Necrotising otitis externa is associated with high morbidity and mortality rates. This study investigated whether temporomandibular joint involvement had any prognostic effect on the course of necrotising otitis externa in patients who had undergone...
[Anorectal symptoms after prostate radiotherapy].
Abstract: Prostate cancer is the most common cancer in Dutch men and has a relatively good survival rate. Anorectal symptoms after irradiation of the prostate, including rectal blood loss and faecal incontinence, can have a serious impact on quality of life. On...