Hyperbaric Oxygen Therapy (HBOT) Research for Sarcoma.
Abstract: van der Kleij, Kooijman, Kipp, Obertop, , , , , (1996). Tumour oxygenation: the influence of normobaric and hyperbaric oxygen. Advances in experimental medicine and biology, 1996 ;388():385-90. https://www.ncbi.nlm.nih.gov/pubmed/8798839
Abstract: The contents of oxygen free radicals (OFRs) and malondialdehyde (MDA) in S-180 sarcoma tissues were measured in four groups of mice: an untreated normoxic group, a normoxic hyperbaric group, a hyperbaric oxygen group, and an HBO group treated with superoxide...
Abstract: Perfluorochemical emulsions are being examined in many laboratory and clinical studies as possible adjuncts to radiotherapy and chemotherapy. The studies reported here examine the clinical potential of hyperbaric oxygen (HBO) in combination with a highly...
Abstract: The effect of hyperthermia on radiation carcinogenesis was investigated in the C3Hf/Sed mouse foot. The foot was irradiated under hypoxic conditions, in air, or under hyperbaric oxygen conditions to evaluate the oxygen effect. Hyperthermia at 43.5 degrees C...
Abstract: The study failed to show a stimulating effect of hyperbaric oxygen on growth and metastatic spreading of sarcoma 37 transplanted subcutaneously or intravenously to female SHR mice, melanoma B16 intramuscularly transplanted to female C57/Bl mice and...
Abstract: Therapeutic gain factors (TGFs) have been determined for three spontaneous tumors of the C3H mouse treated by photons + normobaric oxygen (O2(1) ATA), photons + hyperbaric oxygen (O2 3 ATA), photons + misonidazole, or fast neutrons. The tumors were early...
Abstract: In an attempt to improve the antitumor efficacy of bleomycin, the effects of the oxygen-carrying emulsion Fluosol-DA and increased levels of inspired oxygen were tested in the mouse FSaIIC fibrosarcoma system. The dose-dependent cytotoxicity of bleomycin...
Abstract: Adding Fluosol-DA and carbogen breathing to treatment with various anticancer drugs can result in a significant enhancement of tumor growth delay compared to the drug and air breathing. The optimal conditions for tumor response depend upon the drug,...
Abstract: The effect of hyperglycemia (elevated blood glucose level) on the response of a murine tumor to irradiation given alone or in combination with hyperthermia was studied. Tumors were early generation isotransplants of a spontaneous C3H/Sed mouse fibrosarcoma,...