Abstract: Currently wound treatment options of amputation stumps due to purpura fulminans include healing by secondary intention from wound debridement, split-thickness skin grafting, tissue and muscle flaps, plantar skin free transfer, skin expansion, artificial...
Chronic Wounds
Hyperbaric Oxygen Therapy (HBOT) Research for Chronic Wounds.
NOS inhibition increases bubble formation and reduces survival in sedentary but not exercised rats.
Abstract: Previously we have shown that chronic as well as a single bout of exercise 20 h prior to a simulated dive protects rats from severe decompression illness (DCI) and death. However, the mechanism behind this protection is still not known. The present study...
Non-randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema and tissue fibrosis after radiotherapy for early breast cancer.
Abstract: Radiation-induced arm lymphoedema is a common and distressing complication of curative treatment for early breast cancer. Hyperbaric oxygen (HBO(2)) therapy promotes healing in bone rendered ischaemic by radiotherapy, and may help some soft-tissue injuries...
Topical hyperbaric oxygen and electrical stimulation: exploring potential synergy.
Abstract: Treatment of chronic wounds involves interventions ranging from dressings to surgery. Modalities gaining popularity in clinical settings include topical hyperbaric oxygen and electrical stimulation. A prospective, uncontrolled study was conducted to obtain...
Mind-body techniques in wound healing.
Abstract: Even the most skilled and resourceful wound care provider encounters stagnation of wound healing from time to time. Patients with chronic, nonhealing wounds often display negative thought patterns and behavioral tendencies that, in turn, hinder biological...
Improvement in cerebral metabolism in chronic brain injury after hyperbaric oxygen therapy.
Abstract: While no research study has yet demonstrated convincing evidence for the efficacy of Hyperbaric Oxygen Therapy (HBOT) in patients with chronic neurological disorders (CND), anecdotal studies have been supportive of its use in improving healing of the damaged...
How hyperbaric oxygen therapy helps heal chronic wounds.
Abstract: Boykin, , , , , , , , (2002). How hyperbaric oxygen therapy helps heal chronic wounds. Nursing, 2002 Jun;32(6):24. https://www.ncbi.nlm.nih.gov/pubmed/12189979
Débridement. The key initial first step in wound healing.
Abstract: Before addressing a wound, whether it is chronic or acute, clinicians must thoroughly assess the wound and the patient. An acute wound in a patient with normal blood flow and good medical and nutritional condition should go on to heal if appropriate care is...
Adjuncts to preparing wounds for closure: hyperbaric oxygen, growth factors, skin substitutes, negative pressure wound therapy (vacuum-assisted closure).
Abstract: Achieving closure in a chronic wound requires provision of adequate oxygen delivery to the tissue, adequate protein and other nutritional factors, a moist environment, an appropriate inflammatory milieu, dèbridement, and correction of contributing medical...