Abstract: Hyperbaric oxygen (HBO) therapy has been used as an adjunctive therapy for diabetic foot ulcers, although its mechanism of action is not completely understood. Recently, it has been shown that HBO mobilizes the endothelial progenitor cells (EPCs) from bone...
Diabetic Foot Ulcers
Hyperbaric Oxygen Therapy (HBOT) Research for Diabetic Foot Ulcers
Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice.
Abstract: Hyperbaric oxygen (HBO) therapy has been used as an adjunctive therapy for diabetic foot ulcers, although its mechanism of action is not completely understood. Recently, it has been shown that HBO mobilizes the endothelial progenitor cells (EPCs) from bone...
Hyperbaric oxygen therapy as adjunctive treatment of diabetic foot ulcers.
Abstract: The widespread use of HBO as an adjunctive treatment of diabetic foot ulcers has been founded on weak scientific evidence, but the consistency in positive outcomes in trials evaluating HBO on ulcer healing is noteworthy, not least as these results are in...
Antibiotherapy with and without bone debridement in diabetic foot osteomyelitis: A retrospective cohort study.
Abstract: The treatment of diabetic foot osteomyelitis (DFO) is a controversial issue, with disagreement regarding whether the best treatment is surgical or conservative. The purpose of this study was to compare the outcome of patients with DFO who were treated with...
Comment on: Margolis et al. lack of Effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation: a cohort study. Diabetes Care 2013;36:1961-1966.
Abstract: Carter, Fife, Bennett, , , , , , (2013). Comment on: Margolis et al. lack of Effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation: a cohort study. Diabetes Care 2013;36:1961-1966. Diabetes care,...
Response to Comments on: Margolis et al. Lack of effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation: a cohort study. Diabetes Care 2013;36:1961-1966.
Abstract: Margolis, Gupta, Hoffstad, Papdopoulos, Thom, Mitra, , , (2013). Response to Comments on: Margolis et al. Lack of effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation: a cohort study. Diabetes...
Plantar pressures, plantar forces, and their influence on the pathogenesis of diabetic foot ulcers: a review.
Abstract: Clinical recommendations for the prevention and healing of diabetic foot ulcers (DFUs) are somewhat clear. However, assessment and quantification of the mechanical stress responsible for DFU remain complex. Different pressure variables have been described in...
Hyperbaric oxygen therapy for diabetic ulcers: systematic review and meta-analysis.
Abstract: Approximately 10-15 percent of individuals with diabetes mellitus develop foot ulcers, which precede 85 percent of amputations. Increased oxygen, through the use of hyperbaric oxygen therapy (HBOT), has been suggested to encourage ulcer healing thus reducing...
Interpretation of the study "Lack of effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation".
Abstract: Le, , , , , , , , (). Interpretation of the study "Lack of effectiveness of hyperbaric oxygen therapy for the treatment of diabetic foot ulcer and the prevention of amputation". Undersea & hyperbaric medicine : journal of the Undersea and...