Abstract: It has long been recognized that normal healing is dependent on the oxygen gradient in the wound Hypoxia can slow or arrest the healing process and augments the risk of infection. While hypoxia triggers neoangiogenesis, normal tissue oxygen pressures are...
Diabetic Foot Ulcers
Hyperbaric Oxygen Therapy (HBOT) Research for Diabetic Foot Ulcers
A retrospective study of patients with diabetes mellitus after partial foot amputation and hyperbaric oxygen treatment.
Abstract: Armstrong, Lavery, , , , , , , (). A retrospective study of patients with diabetes mellitus after partial foot amputation and hyperbaric oxygen treatment. The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle...
Intrathecal midazolam combined with low-dose bupivacaine improves postoperative recovery in diabetic mellitus patients undergoing foot debridement.
Abstract: Intrathecal midazolam acts synergically with other anesthetics to relieve surgical pain, and the drug combination may decrease complications attributable to each component drug. This prospective study was to determine the spinal effects of low-dose of...
Evaluation of diabetic wound classifications and a new wound score.
Abstract: We review seven classification systems for foot wounds in patients with diabetes and evaluate them in a table format based on 10 criteria judged to be the most important for assessing their effectiveness. Criteria include such factors as objectivity,...
UHMS position statement: topical oxygen for chronic wounds.
Abstract: A small body of literature has been published reporting the application of topical oxygen for chronic non-healing wounds . Frequently, and erroneously, this form of oxygen administration has been referred to as "topical hyperbaric oxygen therapy"...
Topical hyperbaric oxygen and low-energy laser for the treatment of chronic ulcers.
Abstract: Diabetic foot ulcers (DFU) and chronic venous ulcers (CVU) are persistent cutaneous lesions that are difficult to treat and heal. Topical hyperbaric oxygen (THO) and low-energy laser (LEL) are therapies that have been employed separately for ulcer treatment,...
A retrospective study of patients with diabetes mellitus after partial foot amputation and hyperbaric oxygen treatment.
Abstract: A retrospective chart review was conducted of 35 patients (40 feet) who received hyperbaric oxygen (HBO) therapy after partial foot amputation between 1990 and 2000. Preoperative transcutaneous partial pressure of oxygen (tcPO2) levels, the number of...
Randomized clinical trial comparing OASIS Wound Matrix to Regranex Gel for diabetic ulcers.
Abstract: To compare healing rates at 12 weeks for full-thickness diabetic foot ulcers treated with OASIS Wound Matrix, an acellular wound care product, versus Regranex Gel. Randomized, prospective, controlled multicenter trial at 9 outpatient wound care clinics. A...
Hyperbaric oxygen as an intervention for managing wound hypoxia: its role and usefulness in diabetic foot wounds.
Abstract: Few topics in diabetic wound management generate as much "heated" discussion as hyperbaric oxygen (HBO). Hyperbaric oxygen is an intermittent inhalation therapy in which the patient breathes oxygen at greater than 1 atm of pressure. This requires...