Response to Comments on Fedorko et al. Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial. Diabetes Care 2016;39:392-399.

Abstract: Fedorko, Bowen, Jones, Oreopoulos, Goeree, Hopkins, O'Reilly, , (2016). Response to Comments on Fedorko et al. Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A...

Reliability Assessment of an Innovative Wound Score.

Abstract: The authors describe an innovative wound score and demonstrate its versatility for scoring a variety of wound types in addition to diabetic foot ulcers (DFUs). To further test its merits, they determined its interobserver reliability in a prospective series...

Improved detection of clinically relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers.

Abstract: Clinical wound assessment involves microbiological swabbing of wounds to identify and quantify bacterial species, and to determine microbial susceptibility to antibiotics. The Levine swabbing technique may be suboptimal because it samples only the wound bed,...

Deep tissue biopsy vs. superficial swab culture, including microbial loading determination, in the microbiological assessment of Skin and Soft Tissue Infections (SSTIs).

Abstract: Thirty-two patients affected by SSTIs including DFIs were enrolled between 2013 and 2014. Superficial swab was obtained before and after cleansing with sterile saline, and after ultrasonic debridement; deep tissue biopsy was obtained from ulcer base. Samples...

Changes in vasomotion–effect of hyperbaric oxygen in patients with diabetes Type 2.

Abstract: To investigate vasomotion in diabetic patients who underwent sessions of hyperbaric oxygen (HBO2) therapy. Seventy-one patients with diabetes Type 2 and lower-extremity neuropathy were enrolled in a prospective matched case-control study. A total of 39...

Non-surgical treatment of diabetic foot osteomyelitis.

Abstract: Mutluoglu, Lipsky, , , , , , , (2017). Non-surgical treatment of diabetic foot osteomyelitis. The lancet. Diabetes & endocrinology, 2017 Aug;5(8):668. https://www.ncbi.nlm.nih.gov/pubmed/28108304

Intralesional application of epidermal growth factor in limb-threatening ischemic diabetic foot ulcers.

Abstract: The intralesional injection of recombinant human epidermal growth factor (EGF-IL), a new therapy, has been claimed to prevent major amputations in advanced diabetic foot lesions. In this study, the efficacy of EGF-IL on advanced diabetic foot ulcers (DFU)...

Intralesional application of epidermal growth factor in limb-threatening ischemic diabetic foot ulcers.

Abstract: The intralesional injection of recombinant human epidermal growth factor (EGF-IL), a new therapy, has been claimed to prevent major amputations in advanced diabetic foot lesions. In this study, the efficacy of EGF-IL on advanced diabetic foot ulcers (DFU)...

Calcaneal Osteomyelitis Associated With a Severe Abscess.

Abstract: Diabetic foot osteomyelitis (DFO) is a common complication of the diabetic foot and the majority of minor and major amputations are preceded by DFO. The diagnosis and treatment of DFO are both challenging. Early recognition and comprehensive management of...

Diabetic Foot Ulcers