Abstract: A total of 114 of 195 patients with Crohn's disease had perianal involvement. The average age at the beginning of symptomatology was 30.3 years. The interval between symptoms and diagnosis was 3.1 years. PAC was associated with colonic disease and in these...
Crohn’s Disease
Explore the latest research on the use of Hyperbaric Oxygen Therapy (HBOT) to treat Crohn’s Disease. Extivita maintains an extensive publication database for Crohn’s Disease and various other indications with therapies such as Hyperbaric Oxygen Therapy, Neurofeedback, Nutritional IV Therapy, Infrared Sauna, and Pulsed Electromagnetic Field Therapy. Explore our database on Acne and Hyperbaric Oxygen Therapy aka, HBOT, below.
For a complete list of indications treated at Extivita, explore the conditions we treat.
Six patients whose perianal and ileocolic Crohn’s disease improved in the Dead Sea environment.
Abstract: Hyperbaric oxygen has been used in the management of perianal Crohn's disease on the assumption that tissue oxygenation is impaired. The Dead Sea region of Israel is the lowest point on earth (402 m below sea level), and therefore the oxygen pressure is...
Hyperbaric oxygenation in severe perineal Crohn’s disease.
Abstract: Perineal involvement in Crohn's disease is a common and distressing condition, often refractory to medical or surgical treatments. Recent reports suggest the efficacy of hyperbaric oxygenation (HBO) in the healing of perineal lesions. We evaluated HBO in...
The Role of Chemokines and Chemokine Receptors in Mucosal Inflammation
Recent studies have suggested that nitric oxide (NO.), the product of nitric oxide synthase in inflammatory cells, may play a part in tissue injury and inflammation through its oxidative metabolism
In this study the colonic generation of oxides of nitrogen (NOx) and nitric oxide synthase activity was determined in ulcerative colitis and Crohn’s disease. Colonic biopsy specimens were obtained from inflammatory bowel disease patients and from normal controls. Mucosal explants were cultured in vitro for 24 hours and NOx generation was determined. Nitric oxide synthase activity was monitored by the conversion of [3H]-L-arginine to citrulline. Median NOx generation by inflamed colonic mucosa of patients with active ulcerative colitis and Crohn’s colitis was 4.2- and 8.1-fold respectively higher than that by normal human colonic mucosa.
Hyperbaric oxygen for perianal Crohn’s disease.
Abstract: Perianal involvement in Crohn's disease is common (< or = 50%), distressing, and frequently refractory to treatment. Clinical features include painful induration and stenosis, discharging fistulas, and fissures. The pathogenesis of these lesions is...
Hyperbaric oxygen and perineal Crohn’s disease: a follow-up.
Abstract: Brady (1993). Hyperbaric oxygen and perineal Crohn's disease: a follow-up. Gastroenterology, 1993 Oct;105(4):1264. https://www.ncbi.nlm.nih.gov/pubmed/8405878
[Pneumatosis cystoides intestinalis following steroid treatment in a nephrotic syndrome patient: report of a case].
Abstract: Pneumatosis cystoides intestinalis (PCI) is a relatively rare, benign condition characterized by multiple subserosal or submucosal gas-filled cysts in the bowel wall. The cause and incidence of PCI are uncertain, but the condition is most commonly diagnosed...
[Non-specific ulcerative colitis and Crohn’s disease].
Abstract: The paper is concerned with current status of nonspecific ulcerative colitis and Crohn's disease. Clinical, diagnostic and therapeutic aspects are considered. Crohn's disease was studied in its variants. Hyperbaric oxygenation introduced in combined...
[Hyperbaric oxygenation and drug therapy in treatment of nonspecific ulcerative colitis and Crohn’s disease].
Abstract: Patients with nonspecific ulcerative colitis and Crohn's disease were treated with drug therapy (prednisolone, sulphasalazine, metronidazole per os and hydrocortisone per rectum) and subjected to 12 sessions of HBO. Every 10-14 months the HBO course was...