Rheumatoid Arthritis

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Hyperbaric Oxygen Therapy (HBOT) Research for Rheumatoid Arthritis

Hyperbaric oxygen – its mechanisms and efficacy

Hyperbaric oxygen – its mechanisms and efficacy

Principal mechanisms of HBO2 are based on intracellular generation of reactive species of oxygen and nitrogen. Reactive species are recognized to play a central role in cell signal transduction cascades and the discussion will focus on these pathways. Systematic reviews and randomized clinical trials support clinical use of HBO2 for refractory diabetic wound healing and radiation injuries; treatment of compromised flaps and grafts and ischemia-reperfusion disorders is supported by animal studies and a small number of clinical trials, but further studies are warranted.

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