Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis.

Approximately 1 in 5 adults in the United States are affected by the pain, disability, and decreased quality of life associated with arthritis. The primary focus of treatment is on reducing joint inflammation and pain through a variety of pharmacotherapies, each of which is associated with various side effects. Hyperbaric oxygen therapy is an alternative treatment that has been recommended to treat a variety of inflammatory diseases, ranging from chronic brain injury to exercise induced muscle soreness. The purpose of this set of experiments was to explore the effect of hyperbaric oxygen therapy on joint inflammation and mechanical hyperalgesia in an animal model of arthritis, and compare these effects to treatment with aspirin. Hyperbaric oxygen therapy significantly reduced both joint inflammation and hyperalgesia. As compared with aspirin treatment, hyperbaric treatment was equally as effective in decreasing joint inflammation and hyperalgesia. This article reports that hyperbaric oxygen treatment decreases pain and inflammation in an animal model of arthritis. The effect of hyperbaric oxygen treatment is very similar in magnitude to the effect of acetylsalicylic acid treatment. Potentially, hyperbaric oxygen could be used to treat pain and inflammation in patients with arthritis.

Inflammatory arthritis associated with thromboangiitis obliterans.

Abstract: Thromboangiitis obliterans (TAO) is an uncommon to rare vasculitis of small and medium arteries and veins typically affecting young male smokers. Inflammatory arthritis has only been rarely reported in association with TAO. We describe the case of a young...

Preliminary report of the safety and efficacy of hyperbaric oxygen therapy for specific complications of lung transplantation.

Abstract: Lung transplantation (LTx) is a complex therapy requiring immunosuppression and is associated with significant infective morbidity and mortality. Hyperbaric oxygen (HBO) therapy has been used successfully in the treatment of specific serious infections,...

Rheumatoid arthritis: regulation of synovial inflammation

Abstract Rheumatoid arthritis (RA) is a systemic, inflammatory autoimmune disorder that presents as a symmetric polyarthritis associated with swelling and pain in multiple joints, often initially occurring in the joints of the hands and feet. Articular inflammation...

Pathogenesis and natural history of osteonecrosis.

Abstract: Osteonecrosis (avascular necrosis) is a relatively common disorder seen by both rheumatologists and orthopedic surgeons. The vast majority of cases are secondary to trauma. However, for non-traumatic cases, there often remains a diagnostic challenge in...

Multiple occlusive retinal arteritis in both eyes of a patient with rheumatoid arthritis.

Abstract: To report multiple occlusive retinal arteritis as a complication of rheumatoid arthritis. A 67-year-old woman developed superotemporal branch retinal artery occlusion in both eyes, together with arterial sheathing and large cotton wool patches around the...

Acne with chronic recurrent multifocal osteomyelitis involving the mandible as part of the SAPHO syndrome: case report.

Abstract: For 12 years, a 26-year-old man had acne conglobata and a non-suppurative diffuse sclerosing osteomyelitis of the mandible as part of a chronic recurrent multifocal osteomyelitis of the sternum, the pelvic bones, and the femoral head, and aseptic arthritis...

[Continuous spinal anesthesia in very elderly patients with high anesthesia risk in traumatologic-orthopedic and general surgery interventions].

Abstract: Continuous spinal anaesthesia (CSA) was carried out via a 28-gauge spinal catheter in 154 surgical patients at the Department of Anaesthesiology and Critical Care at Radeberg Asklepios-ASB Hospital between May 1992 and March 1999. The method was used...

Hyperbaric oxygen therapy elicits acute arthritis attack and exacerbation of infection in a patient with infected tophaceous gout and vascular insufficiency.

Abstract: Kung, Tsai, Tsai, Huang, Tsai, Yu, , , (). Hyperbaric oxygen therapy elicits acute arthritis attack and exacerbation of infection in a patient with infected tophaceous gout and vascular insufficiency. Clinical and experimental rheumatology,...

Rheumatoid Arthritis