Abstract: Hyperbaric oxygen (HBO) has been shown to be effective in preventing neurological injuries in animal models of ischaemia, whereas iloprost (IL) prevents ischaemia-related mitochondrial dysfunction and reduces infarction size after focal cerebral ischaemia in...
Spinal Cord Injuries
Hyperbaric Oxygen Therapy (HBOT) Research for Spinal Cord Injuries
Effects of hyperbaric oxygen on MMP-2 and MMP-9 expressions and spinal cord edema after spinal cord injury.
Abstract: To evaluate the effects of hyperbaric oxygen (HBO) therapy on MMP-2 and MMP-9 expressions and spinal cord edema after acute spinal cord injury (SCI). Ninety-six healthy adult Sprague-Dawley rats were randomly divided into 4 groups: sham, sham+HBO, SCI, and...
Effect of preconditioning with hyperbaric oxygen on neural cell apoptosis after spinal cord injury in rats.
Abstract: The aim of this study was to study the effect of preconditioning with hyperbaric oxygen on neural cell apoptosis after spinal cord injury in rats at different times, and to study the mechanism of neuroprotection with hyperbaric oxygen preconditioning after...
Relation between cervical and thoracic spinal canal stenosis and the development of spinal cord decompression sickness in recreational scuba divers.
Abstract: Retrospective case-control study. The intent of this study was to investigate the relationships between vertebral degenerative changes resulting in spinal canal stenosis, spinal cord lesions and the development of spinal cord decompression sickness (DCS) in...
Effects of hyperbaric oxygen on pain-related behaviors and nitric oxide synthase in a rat model of neuropathic pain.
Abstract: Neuropathic pain is complex, and a satisfactory therapeutic method of treatment has yet to be developed; therefore, finding a new and effective therapeutic method is an important issue in the field of neuropathic pain. To determine the effects of hyperbaric...
The therapeutic role of interleukin-10 after spinal cord injury.
Abstract: Spinal cord injury (SCI) is a devastating condition affecting 270,000 people in the United States. A potential treatment for decreasing the secondary inflammation, excitotoxic damage, and neuronal apoptosis associated with SCI, is the anti-inflammatory...
The therapeutic role of interleukin-10 after spinal cord injury.
Abstract: Spinal cord injury (SCI) is a devastating condition affecting 270,000 people in the United States. A potential treatment for decreasing the secondary inflammation, excitotoxic damage, and neuronal apoptosis associated with SCI, is the anti-inflammatory...
Hyperbaric oxygen therapy provides neuroprotection following spinal cord injury in a rat model.
Abstract: To investigate the effect of hyperbaric oxygen therapy (HBOT) on the iNOS mRNA-iNOS-NO signaling pathway and neurofunction protected in a rat spinal cord injury model. A total of 36 Sprague-Dawley rats were randomly divided into 3 groups: control group...
Effects of ultra-early stage hyperbaric oxygenation on the hind limb bone mineral density in rats after complete spinal cord transection.
Abstract: To study the effects of ultra-early stage hyperbaric oxygenation on the hind limb bone mineral density in rats after complete spinal cord transection. 55 SD rats were randomly assigned into three groups: sham-operated group (Sham); complete spinal cord...