Abstract: The therapeutic use of pure oxygen, even under hyperbaric conditions, has been well established for about 50 years, whereas the discovery of oxygen occurred 250 years earlier. Many neurosurgical patients suffer from brain tissue damage, due to reduced blood...
Stroke
Hyperbaric Oxygen Therapy (HBOT) Research for Stroke
Oxygen therapy in stroke: past, present, and future.
Abstract: Oxygen is frequently administered to patients with suspected stroke. However, the role of oxygen therapy in ischemic stroke remains controversial in light of the failure of three clinical trials of hyperbaric oxygen therapy to show efficacy, and the fear of...
Major neurological events following foam sclerotherapy.
Abstract: This report describes two complications of severe neurologic alterations (TIA, CVA) after foamed sclerotherapy injection. Using foam sclerotherapy in accepted concentrations, volume, and in standard ratio of air to sclerosant, two serious neurologic...
Effect of large dose hyperbaric oxygenation therapy on prognosis and oxidative stress of acute permanent cerebral ischemic stroke in rats.
Abstract: To evaluate the therapeutic effect and the oxidative stress effect of 9 and 18 hour hyperbaric oxygenation therapy (HBOT) protocols on the earliest stage of acute permanent middle cerebral artery occlusion (MCAO) in rats. The permanent MCAO model of rats was...
Inappropriate suggestion of benefit from hyperbaric oxygen for spinal cord injury.
Abstract: New, , , , , , , , (2008). Inappropriate suggestion of benefit from hyperbaric oxygen for spinal cord injury. Spinal cord, 2008 Dec;46(12):824. https://www.ncbi.nlm.nih.gov/pubmed/18504450
Viewpoint: the type A- and the type B-variants of Decompression Sickness.
Abstract: Symptoms of neurological decompression incidents (DCS/AGE) can be severe or mild. It is unknown if these differences of symptom presentation represent different clinical entities or if they represent just the spectrum of DCS/AGE. 267 cases with DCS/AGE were...
Paradoxical air embolism successfully treated with hyperbaric oxygen.
Abstract: The use of the central venous catheter may be complicated by air embolism when central venous pressure is subatmospheric and the catheter is open to the surrounding air. Paradoxical air embolus occurs when the gas bubbles are able to traverse a right to left...
The effect of hyperbaric oxygen therapy on blood vessel function in diabetes mellitus.
Abstract: Prolonged untreated diabetes mellitus leads to microangiopathy, tissue hypoxia and ischemic lesions; it increases the risk for stroke and exacerbates brain tissue damage following ischemia. Patients exhibit advanced atherosclerosis in coronary and cerebral...
Hyperbaric oxygen reduces tissue hypoxia and hypoxia-inducible factor-1 alpha expression in focal cerebral ischemia.
Abstract: The usefulness of hyperbaric oxygen (HBO) and normobaric hyperoxia in acute ischemic stroke is being reexplored because both improve outcome in experimental cerebral ischemia. However, even the basic mechanisms underlying oxygen therapy are poorly...