Abstract: Susac's syndrome is an extremely rare clinical manifestation characterized by the triad of fluctuating sensorineural hearing loss, sudden visual loss and encephalopathy. Probably underdiagnosed, it affects young women who start the clinical history with...
Stroke
Hyperbaric Oxygen Therapy (HBOT) Research for Stroke
Acute psychosis associated with diving.
Abstract: There are only a few reported cases of psychiatric disorders presenting a s decompression sickness (DCS). Previous reports indicate that DCS can result in personality change, depression, Munchausen's syndrome, and pseudo stroke. We report two cases of acute...
Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental stroke.
Abstract: Hyperbaric oxygen therapy is considered an important stroke treatment strategy. To determine whether normobaric oxygen is neuroprotective, and, if so, what the therapeutic time window is. Experiment 1-Serial diffusion- and perfusion-weighted MRI (DWI and...
The pathophysiology of cerebral arterial gas embolism.
Abstract: Bubbles are introduced to the arterial circulation in many patients undergoing cardiac surgical procedures, and some of these distribute to the cerebral vessels. Larger bubbles may arrest in cerebral arterioles, causing ischemia and neuronal injury in the...
Pulmonary barotrauma-induced cerebral arterial gas embolism with spontaneous recovery: commentary on the rationale for therapeutic compression.
Abstract: Pulmonary barotrauma-induced cerebral arterial gas embolism (CAGE) continues to complicate compressed gas diving activities. Inadequate lung ventilation secondary to inadvertent breath holding or rapid buoyant ascent can quickly generate a critical state of...
Hyperbaric oxygenation mitigates focal cerebral injury and reduces striatal dopamine release in a rat model of transient middle cerebral artery occlusion.
Abstract: The usefulness of the administration of hyperbaric oxygen (HBO) in the treatment of acute focal cerebral ischemia remains debatable. A significant association exists between focal cerebral injury and an excessive release of extracellular dopamine (DA). In...
[Hemodynamic and respiratory changes in athletes during deep breath-hold diving].
Abstract: The study analysed the hemodynamic and respiratory aspects of deep breath-hold diving. One male (59-year-old) and one female (32-year-old) subject were enrolled. They were both champion deep breath-hold divers. The dives were performed in the wet compartment...
Down regulation of COX-2 is involved in hyperbaric oxygen treatment in a rat transient focal cerebral ischemia model.
Abstract: The effect of hyperbaric oxygen (HBO) on cyclooxygenase-2 (COX-2) expression after transient focal ischemia was evaluated. A rat middle cerebral artery occlusion/reperfusion (MCAO) model was produced using the intraluminal filament method. After 2 h of...
Hyperbaric oxygen preconditioning induces neuroprotection against ischemia in transient not permanent middle cerebral artery occlusion rat model.
Abstract: This study was designed to determine if repeated hyperbaric oxygen (HBO) exposure induces ischemic tolerance in focal cerebral ischemia. Sixty male SD rats were used in this study. Thirty animals underwent transient middle cerebral artery occlusion (MCAO)...