Burns
A thermal burn is a type of burn resulting from making contact with heated objects, such as boiling water, steam, hot cooking oil, fire, and hot objects. Scalds are the most common type of thermal burn suffered by children, but for adults thermal burns are most commonly caused by fire. Conditions of thermal burns are a reddened to leathered skin condition; burn site pain; swelling; blistering, sometimes glossy from leaking fluid; skin loss or charring with patches appearing white, brown, or black. Burns are generally classified from first degree to fourth degree. However, thermal burns are most commonly categorized as minor, moderate, and major, based almost solely on the depth and size of the burn. Statistics from the American Burn Association (2015) report 73% of burns occur in the home, with males twice as likely to experience burns than females.
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Research
Dorsal black skin necrosis in a Vietnamese pot-bellied pig.
Abstract: Thermal burns are an uncommon cause of injury in large animals. A 10-month-old pet female black and white Vietnamese pot-bellied pig presented to the emergency service with fever and erythematous to purpuric skin lesions affecting the intermandibular space...
Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?
Abstract: The aim of this study was to explore the impact of augmented creatinine clearance and differing minimum inhibitory concentrations (MIC) on piperacillin pharmacokinetic/pharmacodynamic (PK/PD) target attainment (time above MIC (fT>MIC)) in critically ill...
Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients.
Abstract: The objective of this study was to describe the population pharmacokinetics of cefazolin in plasma and the interstitial fluid of subcutaneous tissue of post-trauma critically ill patients and provide clinically relevant dosing recommendations that result in...