Chronic Obstructive Pulmonary Disease (COPD)
COPD affects more than 10 million persons in the United States, with Chronic Bronchitis accounting for approximately 75% of cases and emphysema accounting for the remaining 25%. The incidence, prevalence, and mortality rates of COPD increase with age and are higher in men, whites, and persons of lower socioeconomic status. Cigarette smoking remains the principal cause of disease in up to 90% of patients with chronic bronchitis and emphysema. However, only 15-20% of smokers develop COPD. Repeated exposure to air pollution, dust, or chemical fumes can also lead to the development of COPD, but the contribution of these factors appears to be minor compared with tobacco use.
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Research
Regulation of myogenesis and skeletal muscle regeneration: effects of oxygen levels on satellite cell activity.
Abstract: Reduced oxygen (O2) levels (hypoxia) are present during embryogenesis and exposure to altitude and in pathologic conditions. During embryogenesis, myogenic progenitor cells reside in a hypoxic microenvironment, which may regulate their activity. Satellite...
Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report.
Abstract: We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic. A 38-years-old man with chronic renal...
Coronary gas embolism during a dive: a case report.
Abstract: A healthy scuba diver presented with a NSTEMI (non-ST segment elevation myocardial infarction), pneumothorax and pneumomediastinum after diving. A 34-year-old woman with no significant medical history presented to the emergency department after an episode of...