Disease Modifying Anti-Rheumatic Drugs (DMARD)
Excerpt Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). They can also be used to in the...
The Hyperoxic-Hypoxic Paradox
Effective metabolism is highly dependent on a narrow therapeutic range of oxygen. Accordingly, low levels of oxygen, or hypoxia, are one of the most powerful inducers of gene expression, metabolic changes, and regenerative processes, including angiogenesis and stimulation of stem cell proliferation, migration, and differentiation.
Association Between Vitamins and Amyotrophic Lateral Sclerosis: A Center-Based Survey in Mainland China
Abstract To date, conflicting results about the role of vitamins in amyotrophic lateral sclerosis (ALS) have been reported along with a lack of systematic studies on all types of serum vitamins in patients with ALS. Moreover, extensive studies have been conducted on...
SMR/Theta Neurofeedback Training Improves Cognitive Performance and EEG Activity in Elderly With Mild Cognitive Impairment: A Pilot Study
Abstract Background: Neurofeedback (NF) training, as a method of self-regulation of brain activity, may be beneficial in elderly patients with mild cognitive impairment (MCI). In this pilot study, we investigated whether a sensorimotor (SMR)/theta NF training could...
Role of Hyperbaric Oxygen Therapy on Microvascular Diabetic Complications and Metabolic Profile among Patients with Type 2 Diabetes Mellitus
No abstract available Al-Rawahi A. Role of Hyperbaric Oxygen Therapy on Microvascular Diabetic Complications and Metabolic Profile among Patients with Type 2 Diabetes Mellitus. Oman Med J. 2020 Jun 1;35(3):e129. doi: 10.5001/omj.2020.47. PMID: 32489679; PMCID:...
Evaluation of the NAD + biosynthetic pathway in ALS patients and effect of modulating NAD + levels in hSOD1-linked ALS mouse models
Abstract Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motor neurons. Astrocytes from diverse ALS models induce motor neuron death in co-culture. Enhancing NAD+ availability, or increasing the expression of the NAD+-dependent...
Psoriasis
Overview Psoriasis is a skin disease that causes red, itchy scaly patches, most commonly on the knees, elbows, trunk and scalp. Psoriasis is a common, long-term (chronic) disease with no cure. It tends to go through cycles, flaring for a few weeks or months, then...
Effect of Neurofeedback on Postural Balance and Attention of Women With Knee Osteoarthritis After Bilateral Total Knee Replacement
Abstract Objective: As life expectancy increases, the incidence of degenerative diseases such as osteoarthritis also increases. Dynamic balance is one of the essential factors that affect the mobility and daily living activity of patients suffering from knee...
Modulation of Cellular Biochemistry, Epigenetics and Metabolomics by Ketone Bodies. Implications of the Ketogenic Diet in the Physiology of the Organism and Pathological States
Abstract Ketone bodies (KBs), comprising β-hydroxybutyrate, acetoacetate and acetone, are a set of fuel molecules serving as an alternative energy source to glucose. KBs are mainly produced by the liver from fatty acids during periods of fasting, and prolonged or...