Evaluation of the NAD + biosynthetic pathway in ALS patients and effect of modulating NAD + levels in hSOD1-linked ALS mouse models
Abstract Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motor neurons. Astrocytes from diverse ALS models induce motor neuron death in co-culture. Enhancing NAD+ availability, or increasing the expression of the NAD+-dependent...
Psoriasis
Overview Psoriasis is a skin disease that causes red, itchy scaly patches, most commonly on the knees, elbows, trunk and scalp. Psoriasis is a common, long-term (chronic) disease with no cure. It tends to go through cycles, flaring for a few weeks or months, then...
Effect of Neurofeedback on Postural Balance and Attention of Women With Knee Osteoarthritis After Bilateral Total Knee Replacement
Abstract Objective: As life expectancy increases, the incidence of degenerative diseases such as osteoarthritis also increases. Dynamic balance is one of the essential factors that affect the mobility and daily living activity of patients suffering from knee...
Modulation of Cellular Biochemistry, Epigenetics and Metabolomics by Ketone Bodies. Implications of the Ketogenic Diet in the Physiology of the Organism and Pathological States
Abstract Ketone bodies (KBs), comprising β-hydroxybutyrate, acetoacetate and acetone, are a set of fuel molecules serving as an alternative energy source to glucose. KBs are mainly produced by the liver from fatty acids during periods of fasting, and prolonged or...
Hyperbaric oxygen therapy for mild traumatic brain injury persistent postconcussion syndrome: a randomized controlled trial
Abstract: Persistent postconcussion syndrome (PPCS) after mild traumatic brain injury (mTBI) is a significant public health and military problem for which there is limited treatment evidence. The aim of this study was to determine whether forty 150 kPa hyperbaric...
Hyperbaric oxygen therapy improves neurocognitive functions of post-stroke patients – a retrospective analysis.
Abstract: BackgroundPrevious studies have shown that hyperbaric oxygen therapy (HBOT) can improve the motor functions and memory of post-stroke patients in the chronic stage. ObjectiveThe aim of this study is to evaluate the effects of HBOT on overall cognitive...
The effectiveness of hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorders
Abstract Research based on neuro-imaging findings indicate the presence of cerebral hypoperfusion (decreased blood flow) in children with autism spectrum disorders (ASD). One of modern therapeutic methods that can counteract cerebral hypoperfusion in those children is...
Everything You Need to Know About Water Fasting
Fasting is an ancient practice where people abstain from food (and sometimes drink) for a limited period of time [1]. It’s been part of many cultures for centuries. The reasons behind this practice were mostly of spiritual and religious nature, but people have been...
VEGF and bFGF induction by nitric oxide is associated with hyperbaric oxygen-induced angiogenesis and muscle regeneration
Abstract: Hyperbaric oxygen (HBO) treatment promotes early recovery from muscle injury. Reactive oxygen species (ROS) upregulation is a key mechanism of HBO, which produces high O2 content in tissues through increased dissolution of oxygen at high pressure. Nitric...