Abstract:
Necrotizing soft tissue infection (NSTI) refers to a spectrum of infective diseases characterized by necrosis of the deep soft tissues. Features of manifestation and medical management have been analyzed for association with outcome. The use of hyperbaric oxygen (HBO(2)) therapy has been recommended as an adjunctive treatment but remains controversial. Retrospective cohort study. A major tertiary hospital. All patients admitted with a diagnosis of NSTI across a 5-year period.
Wilkinson, Doolette, , , , , , , (2004). Hyperbaric oxygen treatment and survival from necrotizing soft tissue infection. Archives of surgery (Chicago, Ill. : 1960), 2004 Dec;139(12):1339-45. https://www.ncbi.nlm.nih.gov/pubmed/15611459