Abstract:
To report a pediatric case of posttraumatic fungal fasciitis treated successfully with a combination including posaconazole. Case report. Pediatric critical care unit at Antwerp University Hospital. A 12-yr-old female polytrauma patient, suffering from extensive skin and muscle injuries, developed fasciitis. Two fungi (Mucor and Trichosporon species) were isolated. The necrotic tissues were aggressively excised, hyperbaric oxygen therapy was applied, and oral posaconazole was added to the initial amphotericin B treatment. The patient made an excellent recovery.
De Decker, Van Poucke, Wojciechowski, Ieven, Colpaert, Vogelaers, Jorens, , (2006). Successful use of posaconazole in a pediatric case of fungal necrotizing fasciitis. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006 Sep;7(5):482-5. https://www.ncbi.nlm.nih.gov/pubmed/16878050